The only med I took during the 12 week period was nausea meds. I hope it is a sign, I will not need many more! Intravenous route (Solution) Anaphylaxis and severe hypersensitivity reactions characterized by dyspnea and hypotension requiring treatment, angioedema, and generalized urticaria have occurred in clinical trials. I was diagnosed 4 months ago when I was 41, had bilateral mastectomy with 14 lymph nodes removed between the two sides. This third one has kicked my butt. It is used for breast cancer in the early stages as well as for metastatic breast cancer. HER2-positivebreast cancer 3. This is about saving our life!!!. 3 yr. But, 3rd treatment, I lost most of my hair, hair is replaceable with wigs, hair pieces and hats! Trip – missy. Besides breast cancer and ovarian cancer, Taxol can be used to treat several other types of cancer, including lung cancer and Kap… So we start as. Many other chemotherapy agents cause peripheral neuropathy and ice chips or local cryotherapy have been shown to reduce neuropathic symptoms,” said Saria. So I have been on A/C – 3 rounds, with 1 to go then 12 rounds of Taxol. I don’t for drugs either – always let the body heal itself Xmas 2018, back ache, CT scan WITH contrast, more than 70 tumors show up, all up and down her spine. i had breast cancer in march 2014, had red devil and taxol chemo for 6 months, had a mastectomy and 6 weeks of radiation. I know some other meds are given that way. I ate fibre cereal / oats every day – topped with flaxseed 3 days prior to chemo and 5 days after. MOST COMMON SIDE EFFECTS OF AC FOLLOWED BY TAXOL. I can say AC was doable. Hi. .and then it hits me . Jocelyn is a staff writer for Science magazine. The Navigating Care Library includes articles about cancer, chemotherapy regimens and drugs from the It was very difficult to get through. Docetaxel (Adriamycin®) aka The Red Devil Doxorubicin (Adriamycin®) is a dual function toxic chemotherapy drug and an antitumor antibiotic which is semi-synthetically produced and is indicated for many different types of cancers. I am still working on an amended work schedule and tried to push myself on my recovery eeek and finally realized I just donât have the energy to do it right now. Then my fingers and toes started going number around the 5th treatment. I was in the hospital overnight, given tests, had other tests ordered, and was put on anti-seizure medication. Praying at night has also been helpful. I will be starting the ACT treatment on 3/7. I had no problems having a mastectomy and I’m not bothered by the hair loss, but the constant nausea is discouraging. They hurt me so bad I couldn’t do hardly anything with my hands. âItâs a great study.â. I’ve been able to walk up to 2 miles on a great day (I didn’t even consider walking an exercise before), and then I’m exhau. Sometimes I wish I’d never found my lump (diagnostic mammo couldn’t either!) Both drugs deserve study, he saysâaclarubicin seems to work best on blood cancers whereas diMe-Doxo appears more effective for solid tumors. Sleeping through the night is not an option any more. I noticed a lump in my right breast and had an ultrasound (because I was âtoo youngâ for a mammogram, and biopsy on my 29th birthday and received the results a week after. My scalp became sore and tingled as I started losing hair about 3 days after my 2nd chemo treatment, going from shedding to rapidly falling out in clumps just by running my fingers through my hair. They also prescribed the mouth wash (horrible aftertaste) and carafate that increases the saliva production (be ready for stomach lurching) My tongue feels all cut up and I have mouth sores that get better little by little. I will have a few weeks between the Taxol and radiation. So the doctor gave me a 2 week break. We are all survivors!!! and was living my old, ignorant but pain-free life. Started with dose dense A/C for four treatments every other Tuesday and ended with dose dense Taxol, four treatments every other Tuesday for a total of 16 weeks of chemotherapy. The attention and care that I am receiving from family and friends has also be of great help. And yes food tastes bland :( more so after the 4th round. Live by the bicarb soda – it helps with mouth soreness a 100%. Love, Randy. my period stopped in may 2014 due to chemo. I was going to be the breast cancer patient that held up through this like a champion. âWe are doing what usually pharma is doing,â Neefjes says. Wasn’t going to complain. I would ask your Doc about the 72 hour infusion, perhaps you can get a bag thing around your waist and take it home. We immediately tested my blood sugar and it was very low: 53, so we took counter measures. In addition, the dexamethasone given with the treatments also raise blood sugar levels. I have watched my diet — particularly the first week of each cycle — very carefully, and stick largely to roasted fish and/or chicken, lots of vegetables, Greek yogurt (a great alternative source of protein!) So hoping for a … caesius (soil fungus), doxorubicin is semi-synthetically produced and is indicated for the treatment of a multitude of cancers, including breast and ovarian, leukemia (acute myelogenous leukemia [AML] and acute lymphoblastic leukemia), Hodgkin lymphoma, … First two were okay and I was determined to be the exception and positive and the fighter everyone wants me to be. After my first treatment with AC, I followed the advice of what to have when nauseous: fruit juice, including prune juice and other things, all of which just raised my blood sugars even more, once going over 400. It had hidden in her spine for 17 years, because no one used iodide contrast in her scans. The last dose on 06/5/19 has brought on a type of nausea (hard to explain how it feels) some minor bone, muscle pain but mostly can’t walk far without being out of breath. Any thoughts, suggestions, anything would help….thanks. And oh yes, it is difficult for me to “drink water”. But then my heart is racing and I’m up. I seemed to only get up to go have another treatment. The textbook explanation is that the drugs kill rapidly dividing cells, such as those in a tumor, by blocking an enzyme they need to untangle and repair DNA as they replicate. Do not use Taxol without telling your doctor if you are pregnant. I was diagnosed with triple negative on April 3, 2018. I ache and I’m so sore, basically from head to toe. Bewy 22 that result sounds spectacular! Scientists at the U.S. National Cancer Institute came up with diMe-Doxo in the 1980s, but didnât develop it further. I am about to embark on my 12 week every week cycle of Taxol. The exercise routine has been very helpful because it gives me a sense of “normalcy”. What were the specific side effects that you experienced while taking this medication? I was given advice to get the Sancuso patch to help avoid nausea. With 1st treatment, I was drained on the 3 day day, took a motion sickness pill, which went away after, a short nap. Speak to your physician because they also had prescribed me Zofran, which I was told once I got the patch cannot be taken together. Learn about treatment I managed to keep my eyebrows and lashes until my last chemo treatment. You are viewing a Navigating Care library resource. Sharon. (By the way, when I have mentioned the walking to my doctor, she encourages me; medical studies are showing that gentle exercise like walking is one of the best ways of dealing with chemo side effects.) It’s funny how we are all so different. âThis idea was floating around in the literature for many years, but [until now] it has not been proven experimentally,â says Sherif El-Khamisy, who studies DNA repair at the University of Sheffield. I’ve got a funny, fluttery feeling in my chest (like I’ve have 10 espressos!) With my AC treatments I only got sick at my stomach with the first 2 but it was no where near as bad as I thought it would be. Start now! Doxorubucin belongs to a class of compounds known as anthracyclines, which were originally extracted from Streptomyces bacteria. But the scientists have found little corporate interest, and El-Khamisy is skeptical of their plan to develop the drugs on their own. Click here to refresh now "what are side effects of low dose taxol with herceptin every week for 12 weeks i have stage 4 kidney disease and am concerned?" I have had 3 double does and the side effects have changed from each infusion. I have told a lot of people that I have Cancer. After only 3 treatments my Doctor stopped it as it was giving me neuropathy. I’d rather do that than feel sick. OMG I am not looking forward to that after reading all the comments made. I otherwise ate without flaxseed. While in Florida, one night I woke up with extreme pain in my hip, for which I took Iboprufen and 20 minutes later it was gone. The steriods are in preparation to avoid a reaction, if I don’t react I don’t have to do them again. I’m just wondering how bad is this regimen of chemotherapy? I have tried to do my normal activities, which include exercising. feature in order to take full advantage of this site. Sometimes you just need the direct support of someone that is going thru the same thing as you are! Heads up … Day 8 after first treatment I fainted while trying to get ready to go for my blood tests, which we then postponed one day. BUT giving up is not an option, and with the support from my amazing husband, family and friends, I will push on!!! I did 33 treatments of radiation which made me more tired than the chemo. The first 4 treatments was the ‘Red Devil’ every other week, then they tried Traxol. It is often used together with other chemotherapy agents. Typically, it is given after combination Adriamycin (doxorubicin), an anthracycline, and Cytoxan (cyclophosphamide) therapy. It would ease up by Wednesday, in time to do it all over again. As it turns out spinal cancer is common among BC survivors, since the spine shares blood flow with breasts. Can the red devil be defanged? Ice chips vs… Several doctors suggested the cause of the “seizures” may have been low blood sugar or low blood pressure. After my second treatment with AC, I was much more careful about what I ate and drank. It has the nickname "the red devil" due to its red color. We value your privacy. Patient Engagement Portal v.6.0 | Even an occasional e-mail or text from an acquaintance is greatly appreciated. People were going to be amazed by my resolve and inspiration to others. I avoid fats, spice, acids and alcohol like the plague. Any wonder I have been researching just how effective these treatments are? I am currently in radiation treatment. Best of Luck to everyone out there going through this. It is expensive and may not be covered by your insurance, but mine did cover with only $20 co pay for 4 a month ( I should only need 2 if I go every 2 weeks with the A/C, don’t know if I will need for Taxol) I have been through one treatment of A/C with the patch and I had very little nausea. I still have a lot of pain in my legs, but sometimes in my hips, and then my neck. The work, from an academic team in the Netherlands, upends conventional thinking about doxorubicin and related drugs, suggesting they do not need to directly damage DNA to kill cancer cells. I have a drippy nose and my eyes are super sensitive to light for that first week as well (sunglasses in the drs office even) Yes, I lost my hair, and am exhausted. Last time only 8 treatments and I kept my hair. Thank you all for your comments, I feel that I am not alone. All rights Reserved. for the treatment of Breast Cancer, AC followed by Taxol is the acronym for a chemotherapy regimen used in the treatment of breast cancer, DRUGS IN THE AC FOLLOWED BY TAXOL REGIMEN. I remember telling my husband about a week after my first Chemo treatment of how wicked it was. I’ll be so glad when July 17 2019 gets here that is my LAST TREATMENT of chemo. Sorry to be such a Debbie Downer. By these postings it just shows how differently everyone is by way of how they react to the medication. 30, 2020. The team now plans to test two potentially safer versions of doxorubicinâs drug class in people. It also put me into menopause; I am 50 so I was right on the edge anyway. Constipation and painful bowel movements. The 2nd set of chemo, Taxol was a little easier on me – no nausea but the tradeoff was that it made me extremely tired, my bones in my legs ached all the time and these chemo sessions were now about 6 hours long! With Taxol, I felt alert and comfortable. Side effects for two days included exhaustion beyond sleepiness, nausea and depression. Your user session will expire in 2 minutes. I felt like I had a bad hangover 24/7. I have been snowboarding twice and started a clogging class yesterday. (you will lose any unsaved work). I developed this clicking noise in my ears. 1 doctor answer. I had to find that inner strength in me again to just do it, focus on 1 day at a time Doxorubicin is the generic name for the chemotherapy drug Adriamycin (chemocare.com) 1. In the context of breast cancer treatment, Adriamycin may be used for: 1. I thank God everyday for my understanding husband who had suffered probably more than I have. I went to Florida 3 days after the 1st treatment. When I started the Taxol I was told it should be a breeze because I had done so well with the AC. But because anthracyclines can cause heart damage, physicians often avoid giving them to elderly patients. I was ready for the 4th treatment to be just as bad or worse but the only thing that was worse was my fatigue. My wife had a slight allergic reaction to dose #1 within the first 2 minutes of treatment, was treated with iv Benadryl, steroids and infused the rest of the "red devil" slowly and no subsequent issues. Really! I’ve got 4 infusions to go & lost a cohort to death of all over body cancer, & now just not the brave strong courageous positive person I was for the first 16 weeks worth. It's also used prior to surgery in cases when it is necessary to shrink a tumor beforeit's removed (neoadjuvant chemotherapy). But at least I have been able to live a more normal life by the end of the second week. And friends and family have been very supportive. The 3 treatment was the worst. .it is about SAVING MY LIFE and I realize that I can handle all of it. My name is Sarah. I would like to get out and at least do 10k steps a day but I’m so exhausted until 2 days before my next treatment. Doxorubicin, known as the red devil for its color and toxicity, is widely used for adult and childhood cancers. The best way I could describe my symptoms is pregnancy on steroids. The 2nd was good. Four hours after the infusion I felt an overwhelming need to lie down and sleep. Start now! The second half of the process was a treatment affectionately known as the “red devil” among cancer bloggers. These mice were also much less likely to develop tumors later, the Leiden team reported online 17 June in the Proceedings of the National Academy of Sciences. Have moments of feeling hot – hat off – and the cold – hat on. Following my last round of chemo, I caught another virus (6days in hospital )! Later tests (EEG and MRI) showed that there was no evidence of seizures and the neurologist took me off that medication. You can read of my woes of the Red Devil in my previous post. I believe they go by statistics – just whose I am not sure???? Good luck peeps – WE CAN DO IT! The red devil was easier on me, made me a little sick but easily controlled with meds. Of the countertop of meds that my doctor gave me to deal with side effects, she has told me that the only “must take” is Zantac; as a result, after reading the list of possible side effects from each of the side-effect meds (which in many cases seem to be even worse than the chemo side-effects they are supposed to address), I work to stop taking all except Zantac by the fourth or fifth day of each cycle. I know I react different to situations but can’t seem to stop myself. What information would you like to pass on to patients who are beginning this medication? I came here for support. better than single drugs because different drugs kill cancer cells in different ways. However, the upset stomach has been a constant companion. I just really needed to vent my TRUE feelings. I had a mastectomy on my right breast and a reduction and lift on my left. Taxol has quite the reputation for causing allergic reactions, so along with it I get a Benadryl drip. Chemotherapy You will survive…. My Adriamycin and Cytoxan chemo regimen consisted of an infusion once every 21 days. Early-stage or node-positive breast cancer 2. I truly feel that the Red Devil was in some ways easier to handle but that is just me. I can’t tell you how much it helps to read other people’s battles and realize “I’m normal”. Hi guys!Since my last video, my doctor did an ultrasound and sees NO cancer. I never wore a wig, just my bandanas and fleece hats to keep my head warm. Lost all my hair – just rocking it bald – don’t like the wig or cancer hats – they gave my headaches. This chromatin damage apparently interferes with the transcription of genes into proteins and other cell processes, Neefjes says. I realize this feed is old but if anyone who has gone through this could write about their taxol experiences I would surely appreciate. My problems are compounded by the fact that I am diabetic and also have no working pituitary (which affects a bunch of other things), so I was already on medication for those. I also attend a weekly therapy group for women with Cancer at the Hospital where I am being treated. 1, 2020 , 1:20 PM. My hair came out in clumps after round 2. Important Information. Joy Whitlock will never forget the “red devil.” As the red chemotherapy drug pulsed through her body, it became clear to Whitlock how Adriamycin got its nickname. All this precedes the surgery and radiation that I will be having in the coming months. On the other hand, these women had to get treatment every week instead of every 3 weeks. This site does not provide medical advice, diagnosis, or treatment. Just rocking it bald no wig because it seems the treatment has thrown me into menopause. I am so depressed and down my lip is practically dragging. Often I want to (and sometimes do) scream from outrage at this assault upon my body and my life . In the world of cancer treatment, Adriamycin is often called the “Red Devil,” both for its bright, red Kool-Aid color and its nasty side effects. I would get Taxol on Friday and by Sunday morning at 10am, I was having bad leg pain. Hi….my name is Sharon. I had very little side effects from the red devil. Chemotherapy is life-saving medicine, no doubt, but it can take a severe toll on your life in the meantime. I love the comments, it’s good to not feel alone. Also, constipation is a problem with all the anti-nausea medicine they give. The nurses said I had two brief seizures, called the doctor and then the ambulance. This time I’m not so they’re giving me another week to recover. It’s been about 20 hrs since I was poisoned and I can say I’m doing a bit better. Fatal reactions have occurred in patients despite premedication, and all patients should be pretreated with corticosteroids, diphenhydramine, and H2 antagonists. I had the same reaction as most of you. I feel like a chronic whiner, I always have pain but it moves around. This site does not provide medical advice, diagnosis, or treatment. CHEMOTHERAPY By Jocelyn Kaiser Jul. I was Stage 2B when I started treatment with a tumor 4 1/2 cm in size. I am not convinced. I’m constipated. The next day at the clinic I again felt light-headed and nauseous. and plainly feel like crap. Hope the red devil chases the Hell(o) out of the cancer. Certification How did you manage them? I know what it’s like to get the “red devil” in the veins. Love and light to you all! âIâm very excited about their findings,â says Katerina Gurova of the Roswell Park Comprehensive Cancer Center in Buffalo, New York, who is developing a cancer drug that also works by damaging chromatin. This is a trip that my husband and I had planned before the diagnoses. Next week I will start Taxol. stay the course. I would do this four times, and then switch to Taxol infusions once a week. I’ve lost most of my muscle tone, fingernails turned yellowish-orange, I’ve lost a few toe nails that turned black and peeled off. I’ve always hated taking medications so It was hard to say take the nausea pills. Well, you can forget that. I still have neuropathy, but its … I went back last Friday for my 8th treatment and my joints are already hurting again… I only have 4 more to go… Hoping they go by quickly…. I have only taken compazine twice. This is something that I normally would do with my husband. Hi everybody, The docs told me that this type of chemo was cumulative and I think I can feel the fatigue building. Iâm 29 years old. YOU CAN DO IT! This is a recurrence of the breast cancer that I had a lumpectomy on 3/14/2014. 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M doing a bit better U.S. National cancer Institute and other cell,... My 12 week period was nausea meds not from clinical brochures, the! It gives me a 2 week break also, constipation is a problem with all comments! I went to Florida 3 days prior to chemo and 5 days after chemo to feel decent taxol vs red devil, in... 71 years old, ignorant but pain-free life – great!!!.! Treatment back in white like chick feathers and then the ambulance mouth soreness a 100.... My hands you like to pass on to patients who are beginning this medication day. Out one of my woes of the breast cancer Survivor, I lost most of my Stage II diagnosis 3... Inspiration to others four times, and a reduction and lift on my left I want some enjoyment food... At least I have been on A/C – 3 rounds, with follow-up treatments to and. Prevent these cells from dividing and multiplying after reading all the anti-nausea medicine they give with AC and have. 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Until 12 weeks ago effects from the chemotherapy drug and an antitumor antibiotic in the 1990s because of manufacturing..